Malignant Pleural Mesothelioma is one of the most difficult cancers to treat. Its biology is driven by inflammation, fibrosis, and a highly suppressive tumor environment. This makes it an important target for new ideas. Using our AI-powered drug repurposing platform…
One of the toughest challenges in automated drug repurposing and hypothesis generation is validation. Most AI models are tested on data that already include the answers, which often leads to serious information leakage. The model looks good on paper, but…
A friend of mine recently received an email from a mother whose child has been suffering from Wilson’s disease. The existing drugs have serious side effects and are not very tolerable. She was desperately looking for alternatives. We decided to…
In a previous post, I mentioned that the information hidden in PubMed literature far exceeds what’s available in public databases. Here’s a concrete example from our earlier work — a drug repurposing study for COVID-19 (Nat Mach Intell 7, 602–614…
